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I have had regular urinary tract infections in the past but had a few years without them. I then started feeling the onset on Friday morning and by Friday evening it was full blown. I went to the doctor and was prescribed Nitrofurantoin. To start with I didn't notice the symptoms as they merged with the pain from the urinary tract infections and were quite mild but with each dose I am feeling worse and worse. I have the chills, sweating, headaches, disorientation and constant waves of nausea. The doctor warned me that my pee would be discoloured and that was it. I am considering coming off these pills only 2 days in to a 7 day cycle as for me the side effects are almost worse than the UTI.

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The importance of urease as a virulence factor of Proteus-associated UTIs as well as CAUTIs has been demonstrated in the CBA mouse model.

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After taking this med I have had a constant headache, no appetite, I have stomach pains and I feel exhausted.

Patients with long-term use of nitrofurantoin should be monitored regularly for adverse pulmonary effects.

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The fibrosis was atypical in its distribution and not readily compatible with typical forms of pulmonary fibrosis, and was finally attributed to the long-term use of nitrofurantoin.

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Data sources: Online sources including PubMed, The Cochrane Library, Clinical Evidence, DynaMed, and the National Guideline Clearinghouse were searched in April 2003 using “urinary tract infection” and age limitations (younger than 18 years) where applicable.

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Nitrofurantoin usually is taken two or four times a day for at least 7 days.

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VUR found no significant differences in UTI recurrence rates, renal function, renal scarring, hypertension, or end-stage renal disease.

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We describe the clinical history and the autopsy findings in a 51-year-old woman with lung fibrosis of unknown etiology.

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This medication may rarely cause very serious (possibly fatal) lung problems.

Tell patient drug may impair his adaptation to darkness and light, which may cause difficulty driving at night or through tunnels.

Furadantin is a medication used for the treatment and prevention of urinary tract infections.

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Therefore, the definitive role of Proteus hemolysin during UTIs has not been firmly established.

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The ureters and bladder normally prevent urine from backing up toward the kidneys, and the flow of urine from the bladder helps wash bacteria out of the body.

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Chronic reactions (malaise, dyspnea on exertion, cough, altered pulmonary function) may indicate pneumonitis or pulmonary fibrosis and are more common in patients taking nitrofurantoin for 6 mo or longer.

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Achromycin V, Panmycin, Sumycin), digoxin (Lanoxin), nitrofurantoin (Furadantin, Macrobid, Macrodantin), penicillamine (Cuprimine, Depen Titratable), and vitamins.

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To reduce the development of drug-resistant bacteria and maintain the effectiveness of nitrofurantoin (macrocrystals) and other antibacterial drugs, nitrofurantoin (macrocrystals) should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

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Besides antibiotics, impregnation of catheter material with antiseptics, such as silver compounds, has been studied as a possible preventive measure, with conflicting results on the efficacy of these silver-coated urinary catheters in the prevention of bacteriuria.

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